Ipamorelin
Research compoundaka NNC 26-0161
The clean GH secretagogue. Bumps growth hormone without spiking cortisol or prolactin.
Mechanism
Hits the ghrelin/GH-secretagogue receptor and triggers a natural pulse of growth hormone. The selling point is selectivity: you get the GH pulse without the cortisol and prolactin mess the older GHRPs cause. That's why it's the default now, usually run with CJC-1295.
Regulatory & Safety Status
Never made it to market. Clinical development was dropped, so it's a research chemical. Used widely in the GH-peptide crowd regardless.
Research
Peptides in urology and sexual medicine: clinical effectiveness, dosing, indications, and safety: a narrative review
Peptide Supplements and Their Therapeutic Applications in Sports Medicine
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration
Injectable Peptides in Sports Medicine: A Structured Narrative Review of Evidence, Safety, and Antidoping Implications
Ipamorelin GH secretagogue research
Latest ipamorelin research