Thymosin Alpha-1
Approvedaka Tα1, Zadaxin
Thymic immune-modulating peptide. Approved across much of the world, just not the US.
Mechanism
A natural thymic peptide that ramps up T-cell and innate immune activity. It's used abroad as an immune modulator and even a vaccine adjuvant, with a real clinical track record behind it.
Regulatory & Safety Status
Approved and sold in plenty of countries (Zadaxin) for hepatitis and immune support. Not FDA-approved in the US, where it sits in the research-chemical bucket.
Research
Thymosin Alpha-1 Restores Chemotherapy-Induced Antitumor Immunity by Chaperoning a MicroRNA Ligand of TLR7 in Dendritic Cells
Thymosin α1 combined with immune checkpoint inhibitors: synergistic remodeling of the tumor immune microenvironment to enhance clinical efficacy and safety
Peptide Therapies in Thyroid Health: Emerging Applications in Endocrine and Immune Modulation
Preliminary results from a phase II trial of spatially fractionated radiotherapy combined with immunotherapy and anti-angiogenic therapy in patients with bulky solid tumors: early evidence of promising efficacy and favorable safety
Latest thymosin alpha-1 research