LL-37
Preclinicalaka Cathelicidin, CAP-18 fragment
Your body's own antibiotic. A broad antimicrobial and immune-signalling peptide.
Mechanism
The active fragment of human cathelicidin, a host-defense peptide that kills microbes directly and also runs inflammation, wound healing, and immune signalling. Double-edged though: too much of it is implicated in some inflammatory skin conditions.
Regulatory & Safety Status
Research stage, not approved as a therapeutic. Mostly a lab compound for now.
Research
Virtual screening identifies specnuezhenide as a potential therapeutic agent for rosacea via KLK5/TLR4/NF-κB pathway inhibition and metabolic modulation
Inflammation-Associated Changes in Bioactive Proteins and Peptides of Bovine Milk: Evidence from Mastitis, Lameness, and Metabolic Disorders-A Review
Antimicrobial Peptides of the Skin: Roles in Skin Cancer and Clinical Applications
Human neuronal cells SH-SY5Y as an in vitro model to study Neospora caninum infection and innate immune modulation
Latest LL-37 research